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Although the exact cause of AMD is not known, as the eye ages debris from the retinal pigment epithelial (RPE) cell layer and surrounding tissues accumulates between Bruch’s membrane and the RPE.
The debris form deposits called drusenDrusen
Yellow deposits comprised of cellular debris and other biological material that accumulate underneath the retina as a person ages; an increase in the number and/or size of drusen is associated with the development and progression of Dry AMD
above Bruch’s membrane. The presence of many small drusen or one or a few large drusen is usually the first sign of early dry AMDdry AMD (dry Age-Related Macular Degeneration)
Chronic eye disease that causes vision loss in the center of your field of vision due to deterioration of the macula.
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