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The Science of AMD It's almost the end of Low Vision Awareness Month, so please visit Look To Your Future, a new resource to help you take care of your eyes. Read patient stories, educate yourself on wet AMD and DME and find links to helpful patient organizations:
www.LookToYourFuture.com 4 months ago
The Science of AMD The Science of AMD shared The Angiogenesis Foundation's post. 7 months ago
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The Science of AMD The Science of AMD shared The Angiogenesis Foundation's post. 8 months ago
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The Science of AMD Sustained delivery of ranibizumab with a port delivery system in patients with neovascular age-related macular degeneration has the potential to improve visual outcomes and reduce the treatment burden associated with anti-VEGF injections (presented at the American Society of Retina Specialists meeting).
http://www.healio.com/ophthalmology/retina-vitreous/news/online/%7B47c91ae3-946d-483e-8a2e-eab9f6fea0e2%7D/sustained-delivery-of-ranibizumab-for-amd-may-reduce-treatment-burden 11 months ago
The Science of AMD Treat-and-extend aflibercept therapy for neovascular age-related macular degeneration improved vision and significantly reduced the treatment burden at 2 years (presented at the American Society of Retina Specialists meeting).
io.com/ophthalmology/retina-vitreous/news/online/%7B85299509-224b-4810-b347-a91b141186e4%7D/atlas-study-treat-and-extend-with-aflibercept-reduces-amd-treatment-burden 11 months ago
The Science of AMD Age-related macular degeneration (AMD) is the leading cause of blindness in people 60 and older, and the scary part is there's really nothing that can be done to prevent the condition from developing.
"Everyone 60 and older should have an eye exam every year, especially if they have a family history of AMD," says Dr. Todd Lumsden, an ophthalmologist who specializes in cataract surgery at Eye Consultants in Cape Girardeau. 11 months ago
The Science of AMD Dr. Joshua Mali of The Eye Associates is admired by fellow Manatee and Sarasota county retina specialists for the extent he will go for his patients, a co-worker said of him.
And Mali’s fellow doctors may be envious to learn that in his zeal to save the eyesight of patients who already have dry macular degeneration from getting wet macular degeneration, Mali months ago began studying a piece of technology that has recently been approved by the Federal Drug Administration and Medicare. The technology, called ForeseeHome, is the first FDA-approved home-based monitoring system for macular degeneration patients.
"This machine is like going from the bicycle to the automobile," Mali said, excitedly. "It's streamlined." 11 months ago
The Science of AMD Experts say there are many forms of macular degeneration, and many patients are unaware of the disease until they are diagnosed.
Michael Hellegers of Totowa is 32 and was told by his ophthalmologist six years ago that he was at high risk for the illness, which is also known as AMD — age-related macular degeneration. “I’ve always had bad vision, so I do go for regular exams,” Hellegers says. “But I was surprised when my doctor told me he was very concerned about my right eye. And macular degeneration? My grandmother had it really bad. I knew older people got it, but my doctor said that, based on the images he’d taken, I was absolutely going to get it.” 11 months ago
The Science of AMD Researchers from Buck Institute for Research on Aging enhanced the potency of a compound in broccoli 10x, which could be a possible medication for age-related macular degeneration (AMD).
The researchers discovered that the compound in broccoli, which is called the indole-3-carbinol (I3C), helps clear cells of environmental toxins by activating the aryl hydrocarbon receptor (AhR) protein, which regulates pathways involved in chemical detoxification. AhR, which declines in age, is significant for detoxifying the retina. 11 months ago
The Science of AMD A 2015 study conducted by #HarvardMedicalSchool and #SchepensEyeResearchInstitute, #MassachusettsEyeandEar, Boston, evaluated the effects such AMD issues could have on driving. Driving simulators were used to study the effect of visual blind spots on drivers’ ability to detect and react to potential dangers. The study’s findings indicated that people with central vision blind spots (such as those associated with AMD), experienced delayed reactions to avoid pedestrian hazards. This makes perfect sense given how AMD progresses and damages vision. 12 months ago
The Science of AMD Induced pluripotent stem cells (iPS) were supposed to herald a medical revolution. But ten years after their discovery, they are transforming biological research instead—including cutting-edge research into age-related macular degeneration and other retinal diseases. 12 months ago
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The Science of AMD Silver screen icon Bette Davis once famously pronounced "getting old ain't for sissies." Caring for yourself or a loved one with age-related health issues is no picnic, either. Of all the health issues you may face as you age, vision problems can be particularly devastating. A new study reveals that many people still don't understand the leading cause of legal blindness for older Americans - a condition that could seriously affect their quality of life. 12 months ago
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The Science of AMD Elevated body mass index and presence of geographic atrophy may be associated with a poor response to aflibercept in patients with age-related macular degeneration who were previously treated with ranibizumab or bevacizumab, according to a study. 12 months ago
The Science of AMD These days when I look in the mirror, my face seems to be fading away. I’ve known this could happen for the last 20 years.
I was diagnosed with age-related macular degeneration (AMD) when I was just 39. At the time I had never heard of this disease. Why should I have? AMD was a disease typically diagnosed in people over the age of 55. I was far too young for it to be on my radar.
via Care2 @americanmaculardegenerationfoundation 1 year ago
The Science of AMD As a progressive chronic disease, age-related macular degeneration (AMD) is the leading cause of irreversible vision impairment worldwide. Experimental and clinical evidence has demonstrated that vascular endothelial growth factor (VEGF) plays a vital role in the formation of choroidal neovascularization. Intravitreal injections of anti-VEGF agents have been recommended as a first-line treatment for neovascular AMD.
However, persistent fluid or recurrent exudation still occurs despite standardized anti-VEGF therapy. Patients suffering from refractory or recurrent neovascular AMD may develop mechanisms of resistance to anti-VEGF therapy, which results in a diminished therapeutic effect. Until now, there has been no consensus on the definitions of refractory neovascular AMD and recurrent neovascular AMD. This article aims at clarifying these concepts to evaluate the efficacy of switching drugs, which contributes to making clinical decision more scientifically. Furthermore, insight into the causes of resistance to anti-VEGF therapy would be helpful for developing possible therapeutic approaches, such as combination therapy and multi-target treatment that can overcome this resistance. 1 year ago Log in to like
The Science of AMD Researchers examined the 5-year outcomes of using the drugs Avastin and Lucentis to treat age-related macular degeneration. The results showed that almost half of the participants had 20/40 vision or better, confirming the long-term benefits of the therapy. 1 year ago
The Science of AMD A recent study delved into the role of C-reactive protein (#CRP), a marker of inflammation, in age-related macular degeneration (#AMD). The study demonstrated by in vitro studies that the monomeric form of the protein contributes to chronic inflammation associated with DMAE protein.
AMD is the leading cause of vision loss in people over 60 years. It is estimated there will be about 196 million people with AMD worldwide by 2020. Local inflammation and the immune system play a crucial role in the development of this disease. The analysis of drusen, deposits of cellular debris that accumulate under the retina characteristic of AMD, shows that it contains inflammatory proteins and other components that mediate the process of local inflammation. 1 year ago
The Science of AMD “Unimaginable outcomes” ushered by era of anti-VEGF drugs for age-related macular degeneration (#AMD): before and after the era of anti-VEGF drugs investigated by NIH-funded study of Avastin and Lucentis.
In a study of nearly 650 people with the eye disease age-related macular degeneration, half still had vision 20/40 or better, typically good enough to drive or to read standard print, after five years of treatment with anti-VEGF drugs that are injected into the eye. The authors of the study, funded by the National Eye Institute (NEI) at the National Institutes of Health, say those outcomes would have been unimaginable about 10 years ago, prior to the drugs' availability. 1 year ago
The Science of AMD Researchers from Angers University Hospital in France have found a link between vitamin D deficiency and AMD, especially in the late-stages of the disease. Emerging from the study is some potentially good news for those suffering with the debilitating disease: according to study author Cedric Annweiler, MD, PhD, “It may…be possible that correction of vitamin D deficiency could improve the prognosis of AMD."
Watch U2’s The Edge to learn more about disease preventing foods and to learn about the work of the Angiogenesis Foundation, visit bit.ly/EatToBeat. 1 year ago
Louise Bourdages Brunette Donnez moi des informations en Français la photobiomodulation,(laser) 1 year ago
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The Science of AMD Smoking appears to be one of the major factors leading to vision-loss, however, it is said that only 10-20 percent patients are aware of this fact. According to the director of the Centre for Sight “smokers are three to four times more at risk of developing AMD than their non-smoking counterparts. This risk of developing AMD almost doubles in non-smokers if they are living with smokers.” http://ow.ly/4n4J61 1 year ago
The Science of AMD A new study reveals that “the retina also uses fatty acid b-oxidation for energy, and that dysregulated lipid and glucose photoreceptor energy metabolism may drive neovascular age-related macular degeneration (AMD).” http://ow.ly/4n4IMi 1 year ago
www.LookToYourFuture.com 4 months ago
...By Caring About Your Vision Today.
If you or someone you know are at risk of eye disease or living with low vision, act now. 4 months ago
The holidays don’t have to mean unhealthy overindulgences followed by a harsh deprivation diet in January. Instead, here’s 4 tips from Dr. William Li on how you can give yourself the gift of better health during the holidays with foods and drinks that are great-tasting and crowd-pleasing: bit.ly/2h5HwuD
@thriveglbl 6 months ago
Donate | The Angiogenesis Foundation
7 months ago
One of the most overlooked complications of diabetes is vision loss. If you’re living with diabetes, learn how you can protect your vision #WorldDiabetesDay 8 months ago
One of the most overlooked complications of diabetes is vision loss. If you’re living with diabetes, learn how you can protect your vision #WorldDiabetesDay 8 months ago
http://www.healio.com/ophthalmology/retina-vitreous/news/online/%7B47c91ae3-946d-483e-8a2e-eab9f6fea0e2%7D/sustained-delivery-of-ranibizumab-for-amd-may-reduce-treatment-burden 11 months ago
Sustained delivery of ranibizumab for AMD may reduce treatment burden
SAN FRANCISCO — Sustained delivery of ranibizumab with a port delivery system in patients with neovascular age-related macular degeneration has the potential to improve visual outcomes and reduce the treatment burden associated with anti-VEGF injections, according to a scientific poster presen... 11 months ago
io.com/ophthalmology/retina-vitreous/news/online/%7B85299509-224b-4810-b347-a91b141186e4%7D/atlas-study-treat-and-extend-with-aflibercept-reduces-amd-treatment-burden 11 months ago
ATLAS study: Treat-and-extend with aflibercept reduces AMD treatment burden
SAN FRANCISCO — Treat-and-extend aflibercept therapy for neovascular age-related macular degeneration improved vision and significantly reduced the treatment burden at 2 years, according to a scientific poster presented here at the American Society of Retina Specialists meeting. “A treat... 11 months ago
"Everyone 60 and older should have an eye exam every year, especially if they have a family history of AMD," says Dr. Todd Lumsden, an ophthalmologist who specializes in cataract surgery at Eye Consultants in Cape Girardeau. 11 months ago
Regular eye exams crucial to identify, treat and slow macular degeneration
11 months ago
And Mali’s fellow doctors may be envious to learn that in his zeal to save the eyesight of patients who already have dry macular degeneration from getting wet macular degeneration, Mali months ago began studying a piece of technology that has recently been approved by the Federal Drug Administration and Medicare. The technology, called ForeseeHome, is the first FDA-approved home-based monitoring system for macular degeneration patients.
"This machine is like going from the bicycle to the automobile," Mali said, excitedly. "It's streamlined." 11 months ago
Dr. Joshua Mali is fighting wet macular degeneration with revolutionary monitoring system
“This machine is like going from the bicycle to the automobile." 11 months ago
Michael Hellegers of Totowa is 32 and was told by his ophthalmologist six years ago that he was at high risk for the illness, which is also known as AMD — age-related macular degeneration. “I’ve always had bad vision, so I do go for regular exams,” Hellegers says. “But I was surprised when my doctor told me he was very concerned about my right eye. And macular degeneration? My grandmother had it really bad. I knew older people got it, but my doctor said that, based on the images he’d taken, I was absolutely going to get it.” 11 months ago
Age-related macular degeneration is something all ages should know about
11 months ago
The researchers discovered that the compound in broccoli, which is called the indole-3-carbinol (I3C), helps clear cells of environmental toxins by activating the aryl hydrocarbon receptor (AhR) protein, which regulates pathways involved in chemical detoxification. AhR, which declines in age, is significant for detoxifying the retina. 11 months ago
Broccoli-Related Compound Could Treat Age-Related Macular Degeneration (AMD)
A new study reveals that a compound in broccoli can treat the age-related macular degeneration, which is the deterioration of the eye's macula. 11 months ago
Driving with Age-related Macular Degeneration
12 months ago
How iPS cells changed the world, and how they may save vision!
12 months ago
Guidance and hope for people living with the most-common age-related vision problem
12 months ago
Higher BMI, geographic atrophy may suggest poor response to therapy
12 months ago
I was diagnosed with age-related macular degeneration (AMD) when I was just 39. At the time I had never heard of this disease. Why should I have? AMD was a disease typically diagnosed in people over the age of 55. I was far too young for it to be on my radar.
via Care2 @americanmaculardegenerationfoundation 1 year ago
Living With Age-Related Macular Degeneration | Care2 Healthy Living
I was diagnosed with age-related macular degeneration (AMD) when I was just 39. At the time I had never heard of this disease. 1 year ago
However, persistent fluid or recurrent exudation still occurs despite standardized anti-VEGF therapy. Patients suffering from refractory or recurrent neovascular AMD may develop mechanisms of resistance to anti-VEGF therapy, which results in a diminished therapeutic effect. Until now, there has been no consensus on the definitions of refractory neovascular AMD and recurrent neovascular AMD. This article aims at clarifying these concepts to evaluate the efficacy of switching drugs, which contributes to making clinical decision more scientifically. Furthermore, insight into the causes of resistance to anti-VEGF therapy would be helpful for developing possible therapeutic approaches, such as combination therapy and multi-target treatment that can overcome this resistance. 1 year ago
Resistance to anti-VEGF therapy in neovascular age-related macular degeneration
1 year ago
Long-term benefits of age-related macular degeneration treatments
1 year ago
AMD is the leading cause of vision loss in people over 60 years. It is estimated there will be about 196 million people with AMD worldwide by 2020. Local inflammation and the immune system play a crucial role in the development of this disease. The analysis of drusen, deposits of cellular debris that accumulate under the retina characteristic of AMD, shows that it contains inflammatory proteins and other components that mediate the process of local inflammation. 1 year ago
The Role of an Inflammatory Protein in Age-related Macular Degeneration has been discovered
The study provides new information on the contribution of the C-reactive protein to the development and progression of the disease. 1 year ago
In a study of nearly 650 people with the eye disease age-related macular degeneration, half still had vision 20/40 or better, typically good enough to drive or to read standard print, after five years of treatment with anti-VEGF drugs that are injected into the eye. The authors of the study, funded by the National Eye Institute (NEI) at the National Institutes of Health, say those outcomes would have been unimaginable about 10 years ago, prior to the drugs' availability. 1 year ago
Age-related macular degeneration before and after the era of anti-VEGF drugs
1 year ago
Watch U2’s The Edge to learn more about disease preventing foods and to learn about the work of the Angiogenesis Foundation, visit bit.ly/EatToBeat. 1 year ago
Low Vit. D Levels Linked to Macular Degeneration Risk
Adults with the lowest levels of circulating vitamin D levels had the highest risk for age-related macular degeneration, particularly late-stage, compared with those with the highest levels. 1 year ago
Smoking Leads to Vision Loss, Ophthalmologists Warn
Cigarette smoking has long been known to cause cardiovascular disease and lung cancer. However, not many people really realize that smoking can... 1 year ago
1 year ago